Taraxerone(Synonyms: 蒲公英赛酮)

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Taraxerone (Synonyms: 蒲公英赛酮) 纯度: ≥98.0%

Taraxerone 是从景天中分离出来的。Taraxerone 增强乙醇脱氢酶 (ADH) 和乙醛脱氢酶 (ALDH) 活性,EC50 值分别为 512.42 μM 和 500.16 μM。

Taraxerone(Synonyms: 蒲公英赛酮)

Taraxerone Chemical Structure

CAS No. : 514-07-8

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Taraxerone 相关产品

相关化合物库:

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  • Bioactive Compound Library Plus

生物活性

Taraxerone is isolated from Sedum sarmentosum. Taraxerone enhances effects on alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities with EC50 values of 512.42 and 500.16 μM, respectively[1].

IC50 & Target

EC50: 512.42 μM (ADH); 500.16 μM (ALDH)[1]

体内研究
(In Vivo)

Taraxerone significantly lowers the plasma alcohol and acetaldehyde concentrations in mice. Compare to the control group, the ADH and ALDH expressions in the liver tissues are abruptly increased in the taraxerone-treated groups after ethanol exposure[1].
Taraxerone prevents catalase, superoxide dismutase, and reduces glutathione concentrations from the decrease induced by ethanol administration[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

424.70

Formula

C30H48O

CAS 号

514-07-8

中文名称

蒲公英赛酮

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

参考文献
  • [1]. Sung CK, et al. Taraxerone enhances alcohol oxidation via increases of alcohol dehyderogenase (ADH) and acetaldehyde dehydrogenase (ALDH) activities and gene expressions.Food Chem Toxicol. 2012 Jul;50(7):2508-14.