Acremoxanthone C

天然产物醌类Quinones

Acremoxanthone C 

Acremoxantone C 是一种有效的钙调素 (CaM) 抑制剂,存在于 Purpureocillium lilacinum 中。Acremoxantone C 与人钙调素 (hCaM) 生物传感器 hCaM M124C mBBr 结合,Kd为 18.25 nM。

Acremoxanthone C

Acremoxanthone C Chemical Structure

CAS No. : 1360445-63-1

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生物活性

Acremoxanthone C is a potent calmodulin (CaM) inhibitor found in Purpureocillium lilacinum. Acremoxanthone C binds to the human calmodulin (hCaM) biosensor hCaM M124C-mBBr, with Kd of 18.25 nM[1].

IC50 & Target[1]

Microbial Metabolite

 

分子量

614.55

Formula

C33H26O12

CAS 号

1360445-63-1

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Madariaga-Mazón A, et al. Absolute configuration of acremoxanthone C, a potent calmodulin inhibitor from Purpureocillium lilacinum. J Nat Prod. 2013;76(8):1454-1460.