Resorufin methyl ether(Synonyms: Methoxyresorufin)

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Resorufin methyl ether;(Synonyms: Methoxyresorufin)

Resorufin methyl ether (Methoxyresorufin) 是一种细胞色素 P450 的荧光底物，是啮齿动物中 CYP1A2 特异性底物。

Resorufin methyl etheramp;;(Synonyms: Methoxyresorufin)

Resorufin methyl ether Chemical Structure

CAS No. : 5725-89-3

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生物活性

Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate[1]. Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents[1][2].

分子量

227.22

Formula

C13H9NO3
CAS 号

5725-89-3
中文名称

甲氧基试卤灵
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. P V Nerurkar, et al. Methoxyresorufin and benzyloxyresorufin: substrates preferentially metabolized by cytochromes P4501A2 and 2B, respectively, in the rat and mouse. Biochem Pharmacol. 1993 Sep 1;46(5):933-43.

    [2]. Hansen Murcia, et al. Study on the inhibitory effect of furafylline and troleandomycin in the 7-methoxyresorufin-O-demethylase and nifedipine oxidase activities in hepatic microsomes from four poultry species using high-performance liquid chromatography coupled with fluorescence and ultraviolet detection. J Pharm Biomed Anal. 2019 Feb 5;164:148-154.