Etelcalcetide(Synonyms: AMG 416 KAI-4169)

Etelcalcetide;(Synonyms: AMG 416; KAI-4169)

Etelcalcetide (AMG 416) 是一种合成肽,有钙敏感受体 (CaSR) 活化剂的作用。Etelcalcetide 可有效降低接受血液透析的继发性甲状旁腺功能亢进患者的 甲状旁腺激素 (PTH) 浓度。

Etelcalcetideamp;;(Synonyms: AMG 416;  KAI-4169)

Etelcalcetide Chemical Structure

CAS No. : 1262780-97-1

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1 mg ¥550 询问价格 货期
5 mg ¥2000 询问价格 货期
10 mg ¥3400 询问价格 货期
25 mg ¥6800 询问价格 货期

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Etelcalcetide 的其他形式现货产品:

Etelcalcetide hydrochloride

生物活性

Etelcalcetide (AMG 416) is a synthetic peptide as an activator of the calcium sensing receptor (CaSR). Etelcalcetide is effective in lowering parathyroid hormone (PTH) concentrations in patients receiving dialysis with secondary hyperparathyroidism receiving hemodialysis[1].

Clinical Trial

分子量

1048.25

Formula

C38H73N21O10S2

CAS 号

1262780-97-1

Sequence Shortening

C1′ . Ac-{d-Cys1}-{d-Ala}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Ala}-{d-Arg}-NH2 (Disulfide bridge: Cys1′-Cys1)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.